Recombinant human Nectin 2 protein (Fc Chimera Active) (ab221406)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Active: Yes
- Tags: Fc tag C-Terminus
- Suitable for: Functional Studies, SDS-PAGE, ELISA
Preparation and Storage
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Alternative names
- CD 112
- CD112
- CD112 antigen
see all -
Function
Probable cell adhesion protein. -
Tissue specificity
Ubiquitous. -
Sequence similarities
Belongs to the nectin family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Cell membrane. - Information by UniProt
Images
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Functional Studies - Recombinant human Nectin 2 protein (Fc Chimera Active) (ab221406)
Immobilized ab221406 at 10 μg/mL (100 μL/well) can bind Biotinylated Human TIGIT, Fc Tag, Avi Tag with a linear range of 0.156-2.5 μg/mL.
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Functional Studies - Recombinant human Nectin 2 protein (Fc Chimera Active) (ab221406)Loaded ab221406 on Protein A Biosensor, can bind Human PVRIG with an affinity constant of 0.456 μM as determined in BLI assay.
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Functional Studies - Recombinant human Nectin 2 protein (Fc Chimera Active) (ab221406)Immobilized Human PVRIG at 2 μg/mL (100 μL/well) can bind ab221406 with a linear range of 0.2-3 ng/mL.
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SDS-PAGE - Recombinant human Nectin 2 protein (Fc Chimera Active) (ab221406)SDS-PAGE analysis of reduced ab221406 stained overnight with Coomassie Blue. The reduced protein migrates as 70-80 kDa in SDS-PAGE due to glycosylation.
