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Immunology Innate Immunity Macrophage / Inflamm.

Recombinant Human Macrophage inflammatory protein 5 (ab50223)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Suitable for: Functional Studies, SDS-PAGE

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Description

  • Product name

    Recombinant Human Macrophage inflammatory protein 5
    See all Macrophage inflammatory protein 5 proteins and peptides
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      QFTNDAETEL MMSKLPLENP VVLNSFHFAA DCCTSYISQS IPCSLMKSYF ETSSECSKPG VIFLTKKGRQ VCAKPSGPGV QDCMKKLKPY SI
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab50223 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

      • Reconstitution
        Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use.

      General Info

      • Alternative names

        • C-C motif chemokine 15
        • C-C motif chemokine ligand 15
        • CC chemokine 3
        • CCL15
        • CCL15(29-92)
        • CCL15_HUMAN
        • Chemokine (C C motif) ligand 15
        • Chemokine CC-2
        • Chemokine CC2
        • HCC-2
        • HCC2
        • HMRP 2B
        • HMRP2B
        • Leukotactin 1
        • Leukotactin-1
        • LKN-1
        • LKN1
        • Macrophage inflammatory protein 5
        • MIP 1D
        • MIP-1 delta
        • MIP-1D
        • MIP-5
        • MIP1 delta
        • MIP1d
        • MIP5
        • MRP 2B
        • Mrp-2b
        • Mrp2b
        • NCC 3
        • NCC-3
        • NCC3
        • New CC chemokine 3
        • OTTHUMP00000163955
        • SCYA15
        • SCYL3
        • Small inducible cytokine A15
        • Small inducible cytokine subfamily A (Cys Cys), member 15
        • Small-inducible cytokine A15
        • SY15
        see all
      • Function

        Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15.
      • Tissue specificity

        Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients.
      • Sequence similarities

        Belongs to the intercrine beta (chemokine CC) family.
      • Cellular localization

        Secreted.
      • Target information above from: UniProt accession Q16663 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab50223? Please let us know so that we can cite the reference in this datasheet.

    ab50223 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • C-C motif chemokine 15
      • C-C motif chemokine ligand 15
      • CC chemokine 3
      • CCL15
      • CCL15(29-92)
      • CCL15_HUMAN
      • Chemokine (C C motif) ligand 15
      • Chemokine CC-2
      • Chemokine CC2
      • HCC-2
      • HCC2
      • HMRP 2B
      • HMRP2B
      • Leukotactin 1
      • Leukotactin-1
      • LKN-1
      • LKN1
      • Macrophage inflammatory protein 5
      • MIP 1D
      • MIP-1 delta
      • MIP-1D
      • MIP-5
      • MIP1 delta
      • MIP1d
      • MIP5
      • MRP 2B
      • Mrp-2b
      • Mrp2b
      • NCC 3
      • NCC-3
      • NCC3
      • New CC chemokine 3
      • OTTHUMP00000163955
      • SCYA15
      • SCYL3
      • Small inducible cytokine A15
      • Small inducible cytokine subfamily A (Cys Cys), member 15
      • Small-inducible cytokine A15
      • SY15
      see all
    • Function

      Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15.
    • Tissue specificity

      Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients.
    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession Q16663 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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