Antibodies, Proteins, Kits and Reagents for Life Science

Key features and details

Expression system: Escherichia coli
Purity: > 97% SDS-PAGE
Endotoxin level:
Active: Yes
Suitable for: Functional Studies, HPLC, SDS-PAGE

Alternative names
- C-C motif chemokine 15
- C-C motif chemokine ligand 15
- CC chemokine 3
- CCL15
- CCL15(29-92)
- CCL15_HUMAN
- Chemokine (C C motif) ligand 15
- Chemokine CC-2
- Chemokine CC2
- HCC-2
- HCC2
- HMRP 2B
- HMRP2B
- Leukotactin 1
- Leukotactin-1
- LKN-1
- LKN1
- Macrophage inflammatory protein 5
- MIP 1D
- MIP-1 delta
- MIP-1D
- MIP-5
- MIP1 delta
- MIP1d
- MIP5
- MRP 2B
- Mrp-2b
- Mrp2b
- NCC 3
- NCC-3
- NCC3
- New CC chemokine 3
- OTTHUMP00000163955
- SCYA15
- SCYL3
- Small inducible cytokine A15
- Small inducible cytokine subfamily A (Cys Cys), member 15
- Small-inducible cytokine A15
- SY15
see all
Function

Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15.
Tissue specificity

Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients.
Sequence similarities

Belongs to the intercrine beta (chemokine CC) family.
Cellular localization

Secreted.
Target information above from: UniProt accession Q16663 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

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