Recombinant human LRRK2 (mutated Y1699G) protein (ab204089)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 70% Densitometry
- Active: Yes
- Tags: GST tag N-Terminus
- Suitable for: Functional Studies, SDS-PAGE
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Product name
Recombinant human LRRK2 (mutated Y1699G) protein
See all LRRK2 proteins and peptides -
Biological activity
The specific activity of ab204089 was determined to be 2.6 nmol/min/mg.
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Purity
> 70 % Densitometry. -
Expression system
Baculovirus infected Sf9 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MRHSDSISSLASEREYITSLDLSANELRDIDALSQKCCISVHLEHLEKLE LHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSR NDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN KISGICSPLRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAA MPFLPPSMTILKLSQNKFSCIPEAILNLPHLRSLDMSSNDIQYLPGPAHW KSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCL ENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELHLNFDFKHIGCKAKD IIRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKSDLGMQSA TVGIDVKDWPIQIRDKRKRDLVLNVWDFAGREEFYSTHPHFMTQRALYLA VYDLSKGQAEVDAMKPWLFNIKARASSSPVILVGTHLDVSDEKQRKACMS KITKELLNKRGFPAIRDYHFVNATEESDALAKLRKTIINESLNFKIRDQL VVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVRENQLQLDEN ELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKIMAQILTVKVEG CPKHPKGIISRRDVEKFLSKKRKFPKNYMSQYFKLLEKFQIALPIGEEYL LVPSSLSDHRPVIELPHCENSEIIIRLYEMPGFPMGFWSRLINRLLEISP YMLSGRERALRPNRMYWRQGIYLNWSPEAYCLVGSEVLDNHPESFLKITV PSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDICGEGETLLKKWALYSFN DGEEHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPDLILADLPRN IMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLL RQELVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLT RTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIAD YGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDIL TTGGRIVEGLKFPNEFDELEIQGKLPDPVKEYGCAPWPMVEKLIKQCLKE NPQERPTSAQVFDILNSAELVCLTRRILLPKNVIVECMVATHHNSRNASI WLGCGHTDRGQLSFLDLNTEGYTSEEVADSRILCLALVHLPVEKESWIVS GTQSGTLLVINTEDGKKRHTLEKMTDSVTCLYCNSFSKQSKQKNFLLVGT ADGKLAIFEDKTVKLKGAAPLKILNIGNVSTPLMCLSESTNSTERNVMWG GCGTKIFSFSNDFTIQKLIETRTSQLFSYAAFSDSNIITVVVDTALYIAK QNSPVVEVWDKKTEKLCGLIDCVHFLREVMVKENKESKHKMSYSGRVKTL CLQKNTALWIGTGGGHILLLDLSTRRLIRVIYNFCNSVRVMMTAQLGSLK NVMLVLGYNRKNTEGTQKQKEIQSCLTVWDINLPHEVQNLEKHIEVRKEL AEKMRRTSVE -
Predicted molecular weight
210 kDa including tags -
Amino acids
968 to 2527 -
Modifications
mutated Y1699G -
Tags
GST tag N-Terminus -
Additional sequence information
NM_198578.
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Preparation and Storage
- augmented in rheumatoid arthritis 17
- AURA17
- Dardarin
Images
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SDS-PAGE - Recombinant human LRRK2 (mutated Y1699G) protein (ab204089)
The purity of ab204089 was determined to be >70% by densitometry.
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Functional Studies - Recombinant human LRRK2 (mutated Y1699G) protein (ab204089)Kinase assay showing the specific activity of ab204089 as 2.6 nmol/min/mg.
