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Neuroscience Neurology process Neurodegenerative disease Parkinson's disease Synuclein

Recombinant human LRRK2 protein (ab177261)

Price and availability

194 323 ₸

Availability

Order now and get it on Thursday February 25, 2021

Recombinant human LRRK2 protein (ab177261)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Baculovirus infected Sf9 cells
  • Purity: > 70% Densitometry
  • Active: Yes
  • Tags: proprietary tag N-Terminus
  • Suitable for: Functional Studies, SDS-PAGE

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Description

  • Product name

    Recombinant human LRRK2 protein
    See all LRRK2 proteins and peptides
  • Biological activity

    6 nmol/min/mg

  • Purity

    > 70 % Densitometry.

  • Expression system

    Baculovirus infected Sf9 cells
  • Accession

    Q5S007
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MRHSDSISSLASEREYITSLDLSANELRDIDALSQKCCISVHLEHLEKLE LHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSR NDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN KISGICSPLRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAA MPFLPPSMTILKLSQNKFSCIPEAILNLPHLRSLDMSSNDIQYLPGPAHW KSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCL ENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELHLNFDFKHIGCKAKD IIRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKSDLGMQSA TVGIDVKDWPIQIRDKRKRDLVLNVWDFAGREEFYSTHPHFMTQRALYLA VYDLSKGQAEVDAMKPWLFNIKARASSSPVILVGTHLDVSDEKQRKACMS KITKELLNKRGFPAIRDYHFVNATEESDALAKLRKTIINESLNFKIRDQL VVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVRENQLQLDEN ELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKIMAQILTVKVEG CPKHPKGIISRRDVEKFLSKKRKFPKNYMSQYFKLLEKFQIALPIGEEYL LVPSSLSDHRPVIELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISP YMLSGRERALRPNRMYWRQGIYLNWSPEAYCLVGSEVLDNHPESFLKITV PSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDICGEGETLLKKWALYSFN DGEEHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPDLILADLPRN IMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLL RQELVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLT RTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIAD YGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDIL TTGGRIVEGLKFPNEFDELEIQGKLPDPVKEYGCAPWPMVEKLIKQCLKE NPQERPTSAQVFDILNSAELVCLTRRILLPKNVIVECMVATHHNSRNASI WLGCGHTDRGQLSFLDLNTEGYTSEEVADSRILCLALVHLPVEKESWIVS GTQSGTLLVINTEDGKKRHTLEKMTDSVTCLYCNSFSKQSKQKNFLLVGT ADGKLAIFEDKTVKLKGAAPLKILNIGNVSTPLMCLSESTNSTERNVMWG GCGTKIFSFSNDFTIQKLIETRTSQLFSYAAFSDSNIITVVVDTALYIAK QNSPVVEVWDKKTEKLCGLIDCVHFLREVMVKENKESKHKMSYSGRVKTL CLQKNTALWIGTGGGHILLLDLSTRRLIRVIYNFCNSVRVMMTAQLGSLK NVMLVLGYNRKNTEGTQKQKEIQSCLTVWDINLPHEVQNLEKHIEVRKEL AEKMRRTSVE
    • Predicted molecular weight

      210 kDa including tags
    • Amino acids

      968 to 2527
    • Tags

      proprietary tag N-Terminus

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.50
    Constituents: 0.79% Tris HCl, 0.88% Sodium chloride, 0.31% Glutathione, 0.003% EDTA, 0.005% DTT, 0.002% PMSF, 25% Glycerol (glycerin, glycerine)

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

Images

  • Functional Studies - Recombinant human LRRK2 protein (ab177261)
    Functional Studies - Recombinant human LRRK2 protein (ab177261)
    The specific activity of LRRK2 (ab177261) was determined to be 5.8 nmol/min/mg as per activity assay protocol
  • SDS-PAGE - Recombinant human LRRK2 protein (ab177261)
    SDS-PAGE - Recombinant human LRRK2 protein (ab177261)
    SDS PAGE analysis of ab177261
  • SDS-PAGE - Recombinant human LRRK2 protein (ab177261)
    SDS-PAGE - Recombinant human LRRK2 protein (ab177261)
    SDS PAGE analysis of ab177261
  • Functional Studies - Recombinant human LRRK2 protein (ab177261)
    Functional Studies - Recombinant human LRRK2 protein (ab177261)

    The specific activity of ab177261 was determined to be 6 nmol/min/mg.

  • SDS-PAGE - Recombinant human LRRK2 protein (ab177261)
    SDS-PAGE - Recombinant human LRRK2 protein (ab177261)

    SDS-PAGE analysis of ab177261.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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