Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human Fetuin A protein (ab123466)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 98% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, HPLC, SDS-PAGE

Description

  • Product name

    Recombinant human Fetuin A protein
    See all Fetuin A proteins and peptides

  • Biological activity

    Biological Activity: Determined by its ability to inhibit Cathespin V cleavage of a fluorogenic peptide substrate Z-LR-AMC (RLUs). The expected IC50 is = 100nM.

  • Purity

    > 98 % SDS-PAGE.
    Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    P02765

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      APHGPGLIYR QPNCDDPETE EAALVAIDYI NQNLPWGYKH TLNQIDEVKV WPQQPSGELF EIEIDTLETT CHVLDPTPVA RCSVRQLKEH AVEGDCDFQL LKLDGKFSVV YAKCDSSPDS AEDVRKVCQD CPLLAPLNDT RVVHAAKAAL AAFNAQNNGS NFQLEEISRA QLVPLPPSTY VEFTVSGTDC VAKEATEAAK CNLLAEKQYG FCKATLSEKL GGAEVAVTCT VFQTQPVTSQ PQPEGANEAV PTPVVDPDAP PSPPLGAPGL PPAGSPPDSH VLTVVQPSVG AAAGPVVPPC PGRIRHFKV

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab123466 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        HPLC

        SDS-PAGE

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        For lot specific reconstitution information please contact our Scientific Support Team.

      General Info

      • Alternative names

        • 59 kDa bone sialic acid containing protein
        • A2HS
        • Aa2 066
        • AHS
        • Ahsg
        • Alpha 2 HS glycoprotein
        • Alpha 2 HS glycoprotein chain A
        • Alpha 2 HS glycoprotein chain B
        • Alpha 2 Z globulin
        • Alpha 2HS glycoprotein
        • Alpha-2-HS-glycoprotein chain B
        • Alpha-2-Z-globulin
        • alpha2 Heremans Schmid glycoprotein
        • Asialofetuin
        • Ba alpha 2 glycoprotein
        • Ba-alpha-2-glycoprotein
        • BSP
        • Countertrypin
        • FETUA
        • FETUA_HUMAN
        • Fetuin A
        • Fetuin, mouse, homolog of
        • Fetuin-A
        • FetuinA
        • Glycoprotein PP63
        • HSGA
        • pp63
        see all

      • Function

        Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.

      • Tissue specificity

        Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.

      • Sequence similarities

        Belongs to the fetuin family.
        Contains 2 cystatin fetuin-A-type domains.

      • Post-translational
        modifications

        Phosphorylation sites are present in the extracelllular medium.

      • Cellular localization

        Secreted.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab123466? Please let us know so that we can cite the reference in this datasheet.

    ab123466 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • 59 kDa bone sialic acid containing protein
      • A2HS
      • Aa2 066
      • AHS
      • Ahsg
      • Alpha 2 HS glycoprotein
      • Alpha 2 HS glycoprotein chain A
      • Alpha 2 HS glycoprotein chain B
      • Alpha 2 Z globulin
      • Alpha 2HS glycoprotein
      • Alpha-2-HS-glycoprotein chain B
      • Alpha-2-Z-globulin
      • alpha2 Heremans Schmid glycoprotein
      • Asialofetuin
      • Ba alpha 2 glycoprotein
      • Ba-alpha-2-glycoprotein
      • BSP
      • Countertrypin
      • FETUA
      • FETUA_HUMAN
      • Fetuin A
      • Fetuin, mouse, homolog of
      • Fetuin-A
      • FetuinA
      • Glycoprotein PP63
      • HSGA
      • pp63
      see all

    • Function

      Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.

    • Tissue specificity

      Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.

    • Sequence similarities

      Belongs to the fetuin family.
      Contains 2 cystatin fetuin-A-type domains.

    • Post-translational
      modifications

      Phosphorylation sites are present in the extracelllular medium.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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