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Recombinant Human Claudin18.2 protein (Fc Chimera) (ab276734)

Recombinant Human Claudin18.2 protein (Fc Chimera) (ab276734)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 90% SDS-PAGE
  • Endotoxin level:
  • Tags: Fc tag C-Terminus
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human Claudin18.2 protein (Fc Chimera)
  • Purity

    > 90 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells
  • Accession

    P56856-2
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      DQWSTQDLYN NPVTAVFNYQ GLWRSCVRES SGFTECRGYF TLLGLPAMLQ AVR
    • Predicted molecular weight

      33 kDa including tags
    • Molecular weight information

      The recombinant human CLDN18 consists of 291 amino acids and predicts a molecular mass of 32.8 kDa.
    • Amino acids

      28 to 80
    • Tags

      Fc tag C-Terminus
    • Additional sequence information

      Fc region of human IgG1.Predicted N-terminus: Asp 28.
  • Specifications

    Our Abpromise guarantee covers the use of ab276734 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • Claudin 18
      • Claudin-18
      • CLD18_HUMAN
      • CLDN18
      • SFTA5
      • SFTPJ
      see all
    • Function

      Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
    • Tissue specificity

      Concentrated at the cell-cell borders of epithelial cells.
    • Sequence similarities

      Belongs to the claudin family.
    • Cellular localization

      Cell junction, tight junction. Cell membrane.
    • Target information above from: UniProt accession P56856 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Claudin18.2 protein (ab276734)
    SDS-PAGE - Recombinant Human Claudin18.2 protein (ab276734)
    SDS-PAGE analysis of ab276734

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab276734? Please let us know so that we can cite the reference in this datasheet.

    ab276734 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Claudin 18
    • Claudin-18
    • CLD18_HUMAN

    Images

    • SDS-PAGE - Recombinant Human Claudin18.2 protein (ab276734)
      SDS-PAGE - Recombinant Human Claudin18.2 protein (ab276734)
      SDS-PAGE analysis of ab276734

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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