Recombinant human CD137 protein (ab50088)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, Inhibition Assay
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Product name
Recombinant human CD137 protein
See all CD137 proteins and peptides -
Biological activity
Determined by its inhibitory effect of the TNFSF9 (CD137 ligand) mediated stimulation of IL-8 production by human PBMC. About 90% of inibition was seen using a concentration of 1µg for both TNFSF9 and CD137.
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Purity
> 98 % SDS-PAGE.
The purity is greater than 98% by SDS-PAGE gel and HPLC analyses. -
Expression system
Escherichia coli -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MERTRSLQDP CSNCPAGTFC DNNRNQICSP CPPNSFSSAG GQRTCDICRQ CKGVFRTRKE CSSTSNAECD CTPGFHCLGA GCSMCEQDCK QGQELTKKGC KNCCFGTFND QKRGICRPWT NCSLDGKSVL VNGTKERDVV CGPSPADLSP GASSVTPPAP AREPGHS -
Predicted molecular weight
18 kDa -
Amino acids
19 to 184
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Preparation and Storage
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Alternative names
- 4 1BB
- 4 1BB ligand receptor
- 4-1BB ligand receptor
see all -
Function
Receptor for TNFSF14/4-1BBL. Possibly active during T cell activation. -
Tissue specificity
Expressed on the surface of activated T-cells. -
Sequence similarities
Contains 4 TNFR-Cys repeats. -
Cellular localization
Membrane. - Information by UniProt
