Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human CD137 protein (Fc Chimera Active) (ab215031)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: >= 98% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

Description

  • Product name

    Recombinant human CD137 protein (Fc Chimera Active)
    See all CD137 proteins and peptides

  • Biological activity

    Measured by its binding ability in a functional ELISA.

  • Purity

    >= 98 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    Q07011

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      ERTRSLQDPCSNCPAGTFCDNNRNQICSPCPPNSFSSAGGQRTCDICRQC KGVFRTRKECSSTSNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKGCK DCCFGTFNDQKRGICRPWTNCSLDGKSVLVNGTKERDVVCGPSPADLSPG ASSVTPPAPAREPGHS

    • Predicted molecular weight

      55 kDa including tags

    • Amino acids

      19 to 184

    • Additional sequence information

      The extracellular domain fused to the N-terminus of the Fc region of mouse IgG2a (AAH06196.1).

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab215031 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

        Constituent: 99% PBS

        Lyophilized from 0.2µm-filtered solution in PBS.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        Reconstitute 100 µg vial with 100 µL sterile water to a concentration of 1mg/ml. Add 1X PBS to the desired protein concentration. Working aliquots are stable for up to 3 months when stored at -20°C.

      General Info

      • Alternative names

        • 4 1BB
        • 4 1BB ligand receptor
        • 4-1BB ligand receptor
        • 4-1BB Ligand Receptor T Cell
        • 4-1BB, mouse, homolog of
        • Antigen 4-1BB Homolog
        • CD 137
        • CD137
        • CD137 antigen
        • CDw137
        • HLDA VI
        • Homolog of mouse 4 1BB
        • ILA
        • Induced by lymphocyte activation
        • induced by lymphocyte activation (ILA)
        • Interleukin activated receptor homolog of mouse Ly63
        • Ly63, mouse, homolog of
        • MGC2172
        • OTTHUMP00000044294
        • Receptor protein 4 1BB
        • T cell antigen 4 1BB homolog
        • T cell antigen ILA
        • T-cell antigen 4-1BB homolog
        • T-cell antigen ILA
        • TNF receptor superfamily member 9
        • TNFRSF9
        • TNR9_HUMAN
        • Tumor necrosis factor receptor superfamily member 9
        see all

      • Function

        Receptor for TNFSF14/4-1BBL. Possibly active during T cell activation.

      • Tissue specificity

        Expressed on the surface of activated T-cells.

      • Sequence similarities

        Contains 4 TNFR-Cys repeats.

      • Cellular localization

        Membrane.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab215031? Please let us know so that we can cite the reference in this datasheet.

    ab215031 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • 4 1BB
      • 4 1BB ligand receptor
      • 4-1BB ligand receptor
      • 4-1BB Ligand Receptor T Cell
      • 4-1BB, mouse, homolog of
      • Antigen 4-1BB Homolog
      • CD 137
      • CD137
      • CD137 antigen
      • CDw137
      • HLDA VI
      • Homolog of mouse 4 1BB
      • ILA
      • Induced by lymphocyte activation
      • induced by lymphocyte activation (ILA)
      • Interleukin activated receptor homolog of mouse Ly63
      • Ly63, mouse, homolog of
      • MGC2172
      • OTTHUMP00000044294
      • Receptor protein 4 1BB
      • T cell antigen 4 1BB homolog
      • T cell antigen ILA
      • T-cell antigen 4-1BB homolog
      • T-cell antigen ILA
      • TNF receptor superfamily member 9
      • TNFRSF9
      • TNR9_HUMAN
      • Tumor necrosis factor receptor superfamily member 9
      see all

    • Function

      Receptor for TNFSF14/4-1BBL. Possibly active during T cell activation.

    • Tissue specificity

      Expressed on the surface of activated T-cells.

    • Sequence similarities

      Contains 4 TNFR-Cys repeats.

    • Cellular localization

      Membrane.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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