• Product name

  Recombinant Human APRIL/TNFSF13 protein
  See all APRIL/TNFSF13 proteins and peptides

• Expression system

  Wheat germ

• Protein length

  Full length protein

• Animal free

  No

• Nature

  Recombinant

• • Species

    Human

  • Sequence

    MPASSPFLLAPKGPPGNMGGPVREPALSVALWLSWGAALGAVACAMALLT QQTELQSLRREVSRLQGTGGPSQNGEGYPWQSLPEQSSDALEAWESGERS RKRRAVLTQKQKKQHSVLHLVPINATSKDDSDVTEVMWQPALRRGRGLQA QGYGVRIQDAGVYLLYSQVLFQDVTFTMGQVVSREGQGRQETLFRCIRSM PSHPDRAYNSCYSAGVFHLHQGDILSVIIPRARAKLNLSPHGTFLGL

  • Amino acids

    1 to 247

  • Tags

    GST tag N-Terminus

• Alternative names

  • A proliferation inducing ligand
  • A proliferation-inducing ligand
  • APRIL

  • CD256
  • TALL-2
  • TALL2
  • TNF related death ligand
  • TNF- and APOL-related leukocyte expressed ligand 2
  • TNF-related death ligand 1
  • TNF13_HUMAN
  • TNFSF13
  • TRDL-1
  • TRDL1
  • Tumor necrosis factor (ligand) superfamily, member 13
  • Tumor necrosis factor ligand superfamily member 13
  • Tumor necrosis factor like protein ZTNF2
  • Tumor necrosis factor related death ligand 1
  • UNQ383/PRO715
  • ZTNF2

  see all

• Function

  Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. May be implicated in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.

• Tissue specificity

  Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.

• Sequence similarities

  Belongs to the tumor necrosis factor family.

• Post-translational
  modifications

  The precursor is cleaved by furin.

• Cellular localization

  Secreted.

• Target information above from: UniProt accession O75888 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt