Recombinant Human Angiopoietin 1 protein (denatured) (ab113163)
Key features and details
- Expression system: Escherichia coli
- Purity: > 85% SDS-PAGE
- Suitable for: SDS-PAGE
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Product name
Recombinant Human Angiopoietin 1 protein (denatured)
See all Angiopoietin 1 proteins and peptides -
Purity
> 85 % SDS-PAGE.
ab113163 is purified by using conventional chromatography techniques -
Expression system
Escherichia coli -
Accession
-
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
-
Species
Human -
Sequence
MSNQRRSPENSGRRYNRIQHGQCAYTFILPEHDGNCRESTTDQYNTNALQ RDAPHVEPDFSSQKLQHLEHVMENYTQWLQKLENYIVENMKSEMAQIQQN AVQNHTATMLEIGTSLLSQTAEQTRKLTDVETQVLNQTSRLEIQLLENSL STYKLEKQLLQQTNEILKIHEKNSLLEHKILEMEGKHKEELDTLKEEKEN LQGLVTRQTYIIQELEKQLNRATTNNSVLQKQQLELMDTVHNLVNLCTKE GVLLKGGKREEEKPFRDCADVYQAGFNKSGIYTIYINNMPEPKKVFCNMD VNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQ RQYMLRIELMDWEGNRAYSQYDRFHIGNEKQNYRLYLKGHTGTAGKQSSL ILHGADFSTKDADNDNCMCKCALMLTGGWWFDACGPSNLNGMFYTAGQNH GKLNGIKWHYFKGPSYSLRSTTMMIRPLDF -
Predicted molecular weight
56 kDa -
Amino acids
1 to 480
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Description
Recombinant Human Angiopoietin 1 protein
Preparation and Storage
-
Alternative names
- AGP 1
- AGP1
- AGPT
see all -
Function
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development. -
Sequence similarities
Contains 1 fibrinogen C-terminal domain. -
Post-translational
modificationsGlycosylated. -
Cellular localization
Secreted. - Information by UniProt