Recombinant human 2B4 protein (Tagged) (Biotin) (ab271416)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 90% SDS-PAGE
- Active: Yes
- Tags: Avi tag C-Terminus, Fc tag C-Terminus
- Suitable for: Functional Studies, SDS-PAGE
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Product name
Recombinant human 2B4 protein (Tagged) (Biotin)
See all 2B4 proteins and peptides -
Biological activity
Active in a CD28:2B4-biotin binding assay.
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Purity
>= 90 % SDS-PAGE. -
Expression system
HEK 293 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Predicted molecular weight
52 kDa including tags -
Molecular weight information
Protein runs at higher than predicted MW on SDS-PAGE due to glycosylation. -
Amino acids
22 to 229 -
Tags
Avi tag C-Terminus , Fc tag C-Terminus -
Additional sequence information
Fc region of human IgG1. Genbank: NM_016382. Isoform 1
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Conjugation
Biotin
Preparation and Storage
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Alternative names
- 2B4
- C9.1
- CD244
see all -
Function
Modulate other receptor-ligand interactions to enhance leukocyte activation. -
Tissue specificity
Expressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed not only in NK cells, but also on monocytes and basophils. -
Sequence similarities
Contains 2 Ig-like (immunoglobulin-like) domains. -
Cellular localization
Membrane. - Information by UniProt
Images
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Functional Studies - Recombinant Human 2B4 protein (Tagged) (Biotin) (ab271416)
Functional analysis of ab271416.
Active in a CD28:2B4-biotin binding assay.
Note: CD244 = 2B4
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SDS-PAGE - Recombinant Human 2B4 protein (Tagged) (Biotin) (ab271416)SDS-PAGE analysis of ab271416.
