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Biochemicals Product Range New

R-(+)-Baclofen hydrochloride, GABAB receptor agonist (ab145199)

Key features and details

  • Selective GABAB receptor agonist
  • CAS Number: 63701-55-3
  • Purity: > 98%
  • Soluble in water to 100 mM and in DMSO to 75 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    R-(+)-Baclofen hydrochloride, GABAB receptor agonist
  • Description

    Selective GABAB receptor agonist
  • Biological description

    Selective GABAB receptor agonist. Baclofen (ab120325, ab120149) enantiomer. Acts upstream of the mGluR5 receptor to increase inhibitory neurotransmission. Shows antinociceptive and muscle relaxant effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    63701-55-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (3R)-4-Amino-3-(4-chlorophenyl)butanoic acid hydrochloride
  • Molecular weight

    250.12
  • Molecular formula

    C10H12ClNO2.HCl
  • PubChem identifier

    44601
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM and in DMSO to 75 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC(=CC=C1[C@@H](CC(=O)O)CN)Cl.Cl
  • Source

    Synthetic

  • Research areas

    • Biochemicals
    • Product Range
    • New
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    • Product Range
    • Just Add Water
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    • Chemical Type
    • Biochemicals
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    • Receptors & Transporters
    • GABA
    • GABAB
    • Agonists

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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