Prostaglandin E2, EP1, EP2, EP3, and EP4 ligand (ab144539)
Key features and details
- Potent EP1, EP2, EP3, and EP4 ligand
- CAS Number: 363-24-6
- Purity: > 99%
- Soluble in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Prostaglandin E2, EP1, EP2, EP3, and EP4 ligand -
Description
Potent EP1, EP2, EP3, and EP4 ligand -
Biological description
Potent EP1, EP2, EP3, and EP4 ligand (Kd values are 1 - 10 nM). COX product of arachidonic acid (ab120916). Shows potent vasodilatory and pro-nociceptive effects in vivo. 3D Growth matrix component used in liver and prostate organoid generation.
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Purity
> 99% -
CAS Number
363-24-6 -
Chemical structure
Properties
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Chemical name
(Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid -
Molecular weight
352.47 -
Molecular formula
C20H32O5 -
PubChem identifier
5280360 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1C/C=C\CCCC(=O)O)O)O -
Source
Synthetic
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Research areas