PK11195, benzodiazepine receptor antagonist (ab120378)
Key features and details
- Peripheral benzodiazepine receptor antagonist
- CAS Number: 85532-75-8
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
PK11195, benzodiazepine receptor antagonist -
Description
Peripheral benzodiazepine receptor antagonist -
Biological description
Antagonist at the mitochondrial (peripheral) benzodiazepine receptor (translocator protein, TSPO). Acts as a chemosensitizer of tumor cells to a wide range of chemotherapeutic agents.
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Purity
> 99% -
CAS Number
85532-75-8 -
Chemical structure
Properties
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Chemical name
N-sec-Butyl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide -
Molecular weight
352.86 -
Molecular formula
C21H21ClN2O -
PubChem identifier
1345 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(CC)N(C)C(=O)c2cc1ccccc1c(n2)c3ccccc3Cl -
Source
Synthetic
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Research areas
