Pifithrin-mu, Inhibitor of p53-mediated apoptosis (ab120886)
Key features and details
- Inhibitor of p53-mediated apoptosis
- CAS Number: 64984-31-2
- Purity: > 98%
- Soluble in ethanol to 75 mM and in DMSO to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Pifithrin-mu, Inhibitor of p53-mediated apoptosis -
Description
Inhibitor of p53-mediated apoptosis -
Alternative names
- Antigen NY-CO-13
- BCC7
- Cellular tumor antigen p53
see all -
Biological description
An inhibitor of p53-mediated apoptosis. Prevents p53 binding at the mitochondrial surface without affecting p53 transactivational activities. Pifithrin-μ reduces p53-mediated apoptosis triggered by nutlin; also interacts selectively with HSP70, disrupting its association with many substrate proteins. -
Purity
> 98% -
CAS Number
64984-31-2 -
Chemical structure
