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PD 168393, EGFR inhibitor (ab145187)

Price and availability

134 016 ₸

Availability

Order now and get it on Friday March 05, 2021

Key features and details

  • Potent, irreversible, cell-permeable and selective EGFR inhibitor
  • CAS Number: 194423-15-9
  • Purity: > 98%
  • Soluble in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    PD 168393, EGFR inhibitor
  • Description

    Potent, irreversible, cell-permeable and selective EGFR inhibitor
  • Purity

    > 98%
  • CAS Number

    194423-15-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamide
  • Molecular weight

    369.22
  • Molecular formula

    C17H13BrN4O
  • PubChem identifier

    4708
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br
  • Source

    Synthetic

  • Research areas

    • Tags & Cell Markers
    • Cell Type Markers
    • Tumor Associated
    • Signal Transduction
    • Protein Phosphorylation
    • Tyrosine Kinases
    • Receptor Tyrosine Kinases
    • Signal Transduction
    • Growth Factors/Hormones
    • EGF
    • Cancer
    • Growth factors
    • EGF
    • Cancer
    • Tumor immunology
    • Tumor-associated antigens
    • Cancer
    • Signal transduction
    • Protein phosphorylation
    • Tyrosine kinases
    • Receptor tyrosine kinases
    • Cancer
    • Oncoproteins/suppressors
    • Oncoproteins
    • Growth factor receptors
    • Cancer
    • Tumor biomarkers
    • Oncoproteins
    • Cancer
    • Tumor biomarkers
    • Receptors

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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