Papaverine hydrochloride, PDE10A inhibitor (ab144859)
Key features and details
- Potent, selective PDE10A inhibitor
- CAS Number: 61-25-6
- Purity: > 95%
- Soluble in ethanol and in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Papaverine hydrochloride, PDE10A inhibitor -
Description
Potent, selective PDE10A inhibitor -
Biological description
Potent and selective PDE10A inhibitor (IC50 values are 17 and 284 nM for PDE10A and PDE3A respectively). Shows smooth muscle relaxant, antispasmodic and vasodilatory effects in vivo. Orally active. -
Purity
> 95% -
CAS Number
61-25-6 -
Chemical structure
Properties
-
Chemical name
1-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline hydrochloride -
Molecular weight
375.85 -
Molecular formula
C20H21NO4.HCl -
PubChem identifier
6084 -
Storage instructions
Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
Solubility overview
Soluble in ethanol and in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
COC1=C(C=C(C=C1)CC2=NC=CC3=CC(=C(C=C32)OC)OC)OC.Cl -
Source
Synthetic
-
Research areas
