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Signal Transduction Signaling Pathway Lipid Signaling PLA

PACOCF3, phospholipase A2 inhibitor (ab141761)

Key features and details

  • Selective phospholipase A2 inhibitor
  • CAS Number: 141022-99-3
  • Purity: > 98%
  • Soluble in DMSO to 25 mM and in ethanol to 50 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    PACOCF3, phospholipase A2 inhibitor
  • Description

    Selective phospholipase A2 inhibitor
  • Biological description

    Selective phospholipase A2 inhibitor (IC50 = 3.8 μM). Four times more potent than arachidonyl trifluoromethyl ketone (ab120350). Alters Ca2+ signaling and impairs memory acquisition and retrieval. Active in vitro. Centrally active in vivo.
  • Purity

    > 98%
  • CAS Number

    141022-99-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1,1,1-Trifluoroheptadecan-2-one
  • Molecular weight

    308.40
  • Molecular formula

    C17H31F3O
  • PubChem identifier

    4670
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 25 mM and in ethanol to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCCCCCCCCCCCC(=O)C(F)(F)F
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Signaling Pathway
    • Lipid Signaling
    • PLA
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Phospholipase & Lipase
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Lipid signaling
    • Phospholipase & Lipase
    • Inhibitors

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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