Ozagrel hydrochloride, thromboxane (TXA2) synthetase inhibitor (ab142740)
Key features and details
- Potent and selective thromboxane (TXA2) synthetase inhibitor
- CAS Number: 78712-43-3
- Purity: > 98%
- Soluble in water to 100mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Ozagrel hydrochloride, thromboxane (TXA2) synthetase inhibitor -
Description
Potent and selective thromboxane (TXA2) synthetase inhibitor -
Biological description
Potent and selective thromboxane (TXA2) synthetase inhibitor (IC50 = 4 nM). Shows no inhibitory activity at prostacyclin (PGI2) synthetase, cyclooxygenase or PGE2 isomerase (IC50 > 1 mM). Inhibits platelet aggregation in vitro and arachidonate-induced arterial contraction in vivo. -
Purity
> 98% -
CAS Number
78712-43-3 -
Chemical structure
Properties
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Chemical name
(E)-3-[4-(Imidazol-1-ylmethyl)phenyl]prop-2-enoic acid hydrochloride -
Molecular weight
264.71 -
Molecular formula
C13H12N2O2.HCl -
PubChem identifier
6438130 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC(=CC=C1CN2C=CN=C2)C=CC(=O)O.Cl -
Source
Synthetic
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Research areas