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Epigenetics and Nuclear Signaling DNA methylation DNMTs

O6-Benzylguanine, antineoplastic agent. (ab142739)

Key features and details

  • Guanine analog. Antineoplastic agent.
  • CAS Number: 19916-73-5
  • Purity: > 98%
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    O6-Benzylguanine, antineoplastic agent.
  • Description

    Guanine analog. Antineoplastic agent.
  • Biological description

    Guanine analog. Antineoplastic agent. Forms DNA adducts at the O6 position of guanine. Substrate O6-alkylguanine-DNA alkyltransferase inhibitor. Forms S-benzylcysteine at the active site. Shows antitumor effects in vivo.
  • Purity

    > 98%
  • CAS Number

    19916-73-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    6-Phenylmethoxy-7H-purin-2-amine
  • Molecular weight

    241.25
  • Molecular formula

    C12H11N5O
  • PubChem identifier

    4578
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC=C(C=C1)COC2=NC(=NC3=C2NC=N3)N
  • Source

    Synthetic

  • Research areas

    • Epigenetics and Nuclear Signaling
    • DNA methylation
    • DNMTs
    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Damage & Repair
    • Direct Chemical Reversal
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • DNA, RNA & protein synthesis
    • DNA & RNA synthesis

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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