NSC-632839, ubiquitin isopeptidase inhibitor (ab144599)
Key features and details
- Nonselective ubiquitin isopeptidase inhibitor
- CAS Number: 157654-67-6
- Purity: > 98%
- Soluble in DMSO to 10 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
NSC-632839, ubiquitin isopeptidase inhibitor -
Description
Nonselective ubiquitin isopeptidase inhibitor -
Biological description
Nonselective ubiquitin isopeptidase inhibitor (IC50 values are 45, 37 and 9.8 μM for USP2, USP7 and SENP2 respectively). Induces apoptosome-independent apoptosis and caspase activation. Antitumor agent. -
Purity
> 98% -
CAS Number
157654-67-6 -
Chemical structure
Properties
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Chemical name
3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride -
Molecular weight
339.86 -
Molecular formula
C21H21NO.HCl -
PubChem identifier
5351362 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC=C(C=C1)C=C2CNCC(=CC3=CC=C(C=C3)C)C2=O.Cl -
Source
Synthetic
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Research areas