(-)-Nicotine ditartrate, nicotinic acetylcholine receptor agonist (ab120562)
Key features and details
- Potent nAChR agonist
- CAS Number: 65-31-6
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
(-)-Nicotine ditartrate, nicotinic acetylcholine receptor agonist -
Description
Potent nAChR agonist -
Biological description
Potent nicotinic acetylcholine receptor (nAChR) agonist. Stimulates autonomic ganglia and skeletal muscle neuromuscular junctions. Reduces beta-amyloidosis in a mouse model of Alzheimer's disease. (Ki values are 16.1 (α4β2), 2110 (α7), 520 (α3β4), 270 (α6/α4β4) and 2090 nM (α1β1γδ)).
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Purity
> 99% -
CAS Number
65-31-6 -
Chemical structure
Properties
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Chemical name
(S)-(-)-1-Methyl-2-(3-pyridyl)pyrrolidine (+)-ditartrate salt -
Molecular weight
462.41 -
Molecular formula
C10H14N2.2C4H6O6 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
