Astana Biomed Group, an authorized Abcam distributor in Central Asia

Native Human Alpha Thrombin protein (ab81589)

Key features and details

  • Expression system: Native
  • Purity: > 95% SDS-PAGE
  • Suitable for: Functional Studies, SDS-PAGE

Description

  • Product name

    Native Human Alpha Thrombin protein
    See all Alpha Thrombin proteins and peptides

  • Biological activity

    Specific Activity:

  • Purity

    > 95 % SDS-PAGE.

  • Expression system

    Native

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Native

    • Species

      Human

    • Amino acids

      328 to 622

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab81589 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

      • Form

        Liquid

      • Additional notes

        The active site of thrombin is blocked with Phe-Pro-Arg chloromethylketon (CMK).

      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

        pH: 7.40
        Constituents: 0.476% HEPES, 0.87% Sodium chloride

      General Info

      • Alternative names

        • Coagulation factor II
        • Coagulation factor II (thrombin)
        • F2
        • prothrombin B-chain
        • PT
        • serine protease
        see all

      • Relevance

        Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

      • Cellular localization

        Secreted › extracellular space.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab81589? Please let us know so that we can cite the reference in this datasheet.

    ab81589 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • Coagulation factor II
      • Coagulation factor II (thrombin)
      • F2
      • prothrombin B-chain
      • PT
      • serine protease
      see all

    • Relevance

      Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

    • Cellular localization

      Secreted › extracellular space.

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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