Mouse Galectin 3 ELISA Kit (ab113343)
Key features and details
- Sensitivity: 6 pg/ml
- Range: 8.19 pg/ml - 2000 pg/ml
- Sample type: Cell culture supernatant, Plasma, Serum
- Detection method: Colorimetric
- Assay type: Sandwich (quantitative)
- Reacts with: Mouse
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components 1 x 96 tests 20X Wash Buffer Concentrate 1 x 25ml 400X HRP-Streptavidin Concentrate 1 x 200µl 5X Assay Diluent B 1 x 15ml Assay Diluent A 1 x 30ml Biotinylated anti-Mouse Galectin 3 2 vials Galectin 3 Microplate (12 x 8 wells) 1 unit Recombinant Mouse Galectin 3 Standard (lyophilized) 2 vials Stop Solution 1 x 8ml TMB One-Step Substrate Reagent 1 x 12ml -
Research areas
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Relevance
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis By similarity. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Probably forms homo- or heterodimers. Interacts with DMBT1. Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA. A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Contains 1 galectin domain. -
Cellular localization
Cytoplasmic, Nuclear and Secreted -
Alternative names
- 35 kDa lectin
- Carbohydrate-binding protein 35
- CBP 35
see all -
Database links
- Entrez Gene: 16854 Mouse
- SwissProt: P16110 Mouse
- Unigene: 248615 Mouse
Images
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Representative Standard Curve
Representative Standard Curve using ab113343
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Representative Standard CurveRepresentative Standard Curve using ab113343
