Milrinone, phosphodiesterase 3 inhibitor (ab142322)
Key features and details
- Potent, cell-permeable, selective phosphodiesterase 3 inhibitor
- CAS Number: 78415-72-2
- Purity: > 98%
- Soluble in DMSO to 75 mM and in ethanol to 10 mM (with warming).
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Milrinone, phosphodiesterase 3 inhibitor -
Description
Potent, cell-permeable, selective phosphodiesterase 3 inhibitor -
Biological description
Potent, cell-permeable, selective phosphodiesterase 3 inhibitor (IC50 = 0.42 μM). Inhibits cAMP. Cardiotonic and vasodilator agent. Orally active. Active in vivo and in vitro. -
Purity
> 98% -
CAS Number
78415-72-2 -
Chemical structure
Properties
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Chemical name
6-Methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile -
Molecular weight
211.22 -
PubChem identifier
4197 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 75 mM and in ethanol to 10 mM (with warming). -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=C(C=C(C(=O)N1)C#N)C2=CC=NC=C2 -
Source
Synthetic
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Research areas
