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Biochemicals

Magnolol (5,5'-Diallyl-2,2'-dihydroxybiphenyl), antioxidant (ab142443)

Key features and details

  • Potent antioxidant. Anti-inflammatory and apoptotic agent.
  • CAS Number: 528-43-8
  • Purity: > 98%
  • Soluble in DMSO and in ethanol
  • Form / State: Solid
  • Source: Magnolia officinalis

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Overview

  • Product name

    Magnolol (5,5'-Diallyl-2,2'-dihydroxybiphenyl), antioxidant
  • Description

    Potent antioxidant. Anti-inflammatory and apoptotic agent.
  • Biological description

    Potent antioxidant. Inhibits iNOS expression (IC50 = 16.8 μM). Anti-inflammatory, antioxidative, antitumor, antimicrobial and apoptotic agent. Induces apoptosis by upregulating p53 and bax expression. Honokiol (Asc 647) isomer. Inhibits LPS-induced TNF-α and IL-1β production. Antidepressant and anxiolytic effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    528-43-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-(2-Hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphenol
  • Molecular weight

    266.34
  • Molecular formula

    C18H18O2
  • PubChem identifier

    72300
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO and in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C=CCC1=CC(=C(C=C1)O)C2=C(C=CC(=C2)CC=C)O
  • Source

    Magnolia officinalis

  • Research areas

    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Synthetase & synthase
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Nitric oxide & oxidative stress
    • NOS
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Nitric oxide & oxidative stress
    • Antioxidants
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Immunomodulators & Immunosuppressants
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Antibacterial

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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