Apigenin, Anticancer agent (ab120141)
Key features and details
- Anticancer agent
- CAS Number: 520-36-5
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Apigenin, Anticancer agent -
Description
Anticancer agent -
Biological description
Plant flavone. Antioxidant, anti-inflammatory and anticancer properties. Effects a wide range of molecular targets including caspases, fatty acid synthase, topoisomerase and nuclear factor-κB.
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Purity
> 98% -
CAS Number
520-36-5 -
Chemical structure
Properties
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Chemical name
5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one -
Molecular weight
270.24 -
Molecular formula
C15H10O5 -
PubChem identifier
5280443 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Oc1ccc(cc1)C3=CC(=O)c2c(cc(O)cc2O)O3 -
Source
Synthetic
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Research areas
Images
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Functional Studies - Apigenin, Anticancer agent (ab120141) Bauer et al PLoS One. 2017 Apr 25;12(4):e0175558. doi: 10.1371/journal.pone.0175558. eCollection 2017. Fig 2. Reproduced under the Creative Commons license https://creativecommons.org/publicdomain/zero/1.0/
(A-D). The release of cytokines as assessed using Human Cytokine Array C1000 membranes from MDA-MB-231 cells ± TNFα ± Apigenin. [A] Ctrls, [B] TNFα-treated (40ng/mL) [C] Apigenin (40μM) and [D] TNFα-treated (40ng/mL) + Apigenin (40μM) co-treated cells.
