Kirromycin, Antibiotic agent (ab144287)
Key features and details
- Potent antibiotic agent. Selective EF-Tu inhibitor.
- CAS Number: 50935-71-2
- Purity: > 96%
- Form / State: Solid
- Source: Streptomyces collinus
Overview
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Product name
Kirromycin, Antibiotic agent -
Description
Potent antibiotic agent. Selective EF-Tu inhibitor. -
Biological description
Potent antibiotic agent. Selective EF-Tu inhibitor. Protein synthesis inhibitor. Prevents EF-Tu release from the ribosome. Induces EF-Tu-dependent hydrolysis of GTP in the absence of ribosomes. Shows potent bactericidal effects in vivo. Orally active. -
Purity
> 96% -
CAS Number
50935-71-2 -
Chemical structure
Properties
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Chemical name
(2S)-N-[(2E,4E,6S,7R)-7-[(2S,3S,4R,5R)-5-[(1E,3E,5E,7E)-7-(2,4-dioxo-1H-pyridin-3-ylidene)-7-hydroxy-6-methylhepta-1,3,5-trienyl]-3,4-dihydroxyoxolan-2-yl]-6-methoxy-5-methylocta-2,4-dienyl]-2-[(2R,3R,4R,6S)-2,3,4-trihydroxy-5,5-dimethyl-6-[(1E,3E)-penta-1,3-dienyl]oxan-2-yl]butanamide -
Molecular weight
796.94 -
Molecular formula
C43H60N2O12 -
PubChem identifier
54679334 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC[C@H](C(=O)NC/C=C/C=C(\C)/[C@H]([C@@H](C)[C@H]1[C@H]([C@H]([C@H](O1)/C=C/C=C/C=C(\C)/C(=C\2/C(=O)C=CNC2=O)/O)O)O)OC)[C@@]3([C@@H]([C@@H](C([C@@H](O3)/C=C/C=C/C)(C)C)O)O)O -
Source
Streptomyces collinus
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Research areas