Terazosin hydrochloride dihydrate, Adrenergic alpha-receptor antagonist (ab142601)
Key features and details
- Adrenergic α-receptor antagonist
- CAS Number: 70024-40-7
- Purity: > 98%
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Terazosin hydrochloride dihydrate, Adrenergic alpha-receptor antagonist -
Description
Adrenergic α-receptor antagonist -
Biological description
Adrenergic α-receptor antagonist (Ki values are 3.3, 0.7, 1.1, 7.7, 1510 and 78.2 nM for α1A, α1B, α1D, α2B, α2A and α2C receptors respectively). Tube formation and proliferation inhibitor in tumor cells (IC50 = 6.8 and 9.9 μM, respectively). Antiangiogenic and antitumor agent. Active in vivo and in vitro. -
Purity
> 98% -
CAS Number
70024-40-7 -
Chemical structure
Properties
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Chemical name
[4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone dihydrate hydrochloride -
Molecular weight
459.93 -
Molecular formula
C19H25N5O4.HCl.2H2O -
PubChem identifier
63016 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC.O.O.Cl -
Source
Synthetic
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Research areas
