Indomethacin, Non-selective COX inhibitor (ab120719)
Key features and details
- Non-selective COX inhibitor
- CAS Number: 53-86-1
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 50 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Indomethacin, Non-selective COX inhibitor -
Description
Non-selective COX inhibitor -
Biological description
Non-selective COX inhibitor (IC50 = 230 and 630 nM for human COX-1 and COX-2, respectively). Activates PPARα and PPARγ (EC50 = 40 nM).
-
Purity
> 99% -
CAS Number
53-86-1 -
Chemical structure
Properties
-
Chemical name
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid -
Molecular weight
357.79 -
Molecular formula
C19H16ClNO4 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 50 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
Source
Synthetic
-
Research areas
