Hypericin, PKC inhibitor (ab142440)
Key features and details
- Selective PKC inhibitor. Antiviral agent.
- CAS Number: 548-04-9
- Purity: > 97%
- Soluble in DMSO to 50 mM and in ethanol to 10 mM (with warming)
- Form / State: Solid
- Source: Hypericum perforatum
Overview
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Product name
Hypericin, PKC inhibitor -
Description
Selective PKC inhibitor. Antiviral agent. -
Biological description
Selective PKC inhibitor (IC50 = 3.3 μM). Antiviral agent. Potent tyrosine kinase inhibitor (IC50 = 7.5 μM). Potent CKII inhibitor (IC50 = 6 nM). Inactivates enveloped viruses including HIV. Promotes VEGF and TGF-β production. Shows photosensitizing and antidepressant effects in vivo. -
Purity
> 97% -
CAS Number
548-04-9 -
Chemical structure
Properties
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Chemical name
1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione -
Molecular weight
504.44 -
Molecular formula
C30H16O8 -
PubChem identifier
5281051 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 10 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C=C(C7=C6C5=C3C8=C7C(=CC(=C8C2=O)O)O)O)O)O -
Source
Hypericum perforatum
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Research areas
