Fludarabine phosphate, DNA synthesis inhibitor (ab142731)
Key features and details
- DNA synthesis inhibitor. Antitumor agent.
- CAS Number: 75607-67-9
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Fludarabine phosphate, DNA synthesis inhibitor -
Description
DNA synthesis inhibitor. Antitumor agent. -
Biological description
DNA synthesis inhibitor. Antitumor agent. Interferes with ribonucleotide reductase and DNA polymerase as a purine analogue. Shows antitumor effects in vivo (IC50 = 8-30 μM). Orally active. -
Purity
> 98% -
CAS Number
75607-67-9 -
Chemical structure
Properties
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Chemical name
[(2R,3S,4S,5R)-5-(6-Amino-2-fluoropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate -
Molecular weight
365.21 -
Molecular formula
C10H13FN5O7P -
PubChem identifier
30751 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)O)O)O)N=C(N=C2N)F -
Source
Synthetic
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Research areas
