ICI 118551 hydrochloride, beta2 adrenoceptor antagonist (ab120808)
Key features and details
- Highly selective β2 adrenoceptor antagonist
- CAS Number: 72795-01-8
- Purity: > 99%
- Soluble in water to 10 mM and in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
ICI 118551 hydrochloride, beta2 adrenoceptor antagonist -
Description
Highly selective β2 adrenoceptor antagonist -
Biological description
Highly selective β2 adrenoceptor antagonist (Ki values are 1.2, 120 and 257 nM at β2, β1 and β3 receptors, respectively). Blood-brain barrier permeable. Decreases vascular tone in vivo.
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Purity
> 99% -
CAS Number
72795-01-8 -
Chemical structure
Properties
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Chemical name
(2R*,3R*)-1-[(2,3-Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol -
Molecular weight
313.87 -
Molecular formula
C17H27NO2.HCl -
PubChem identifier
25102594 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 10 mM and in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=C2CCCC2=C(C=C1)OC[C@@H]([C@H](C)NC(C)C)O.Cl -
Source
Synthetic
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Research areas
