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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

Hydrochlorothiazide, Na+-Cl- cotransporter inhibitor (ab142888)

Key features and details

  • Competitive Na+-Cl- cotransporter inhibitor
  • CAS Number: 58-93-5
  • Purity: > 98%
  • Soluble in water to 100 mM (with warming)
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Hydrochlorothiazide, Na+-Cl- cotransporter inhibitor
  • Description

    Competitive Na+-Cl- cotransporter inhibitor
  • Biological description

    Competitive Na+-Cl- cotransporter inhibitor. Diuretic agent. Competes for chloride site of transporter. Reduces sodium reabsorption in the distal convoluted tubule. Shows antihypertensive effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    58-93-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    6-Chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
  • Molecular weight

    297.74
  • Molecular formula

    C7H8ClN3O4S2
  • PubChem identifier

    3639
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM (with warming)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Blood
    • Other
    • Cell Biology
    • Other Antibodies
    • Other Antibodies
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Product Range
    • Just Add Water
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Transporters
    • Ion pumps / transporter
    • Na+ / 2Cl- cotransporter

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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