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Neuroscience Neurology process Neurodegenerative disease Huntington's disease

HA-1077 (Fasudil) (mM/ml), ROCK2 inhibitor (ab146700)

Price and availability

63 657 ₸

Availability

Order now and get it on Friday February 26, 2021

Key features and details

  • ROCK2 inhibitor. 1 ml water soluble pack.
  • CAS Number: 103745-39-7
  • Purity: > 98%
  • Soluble in 1ml of water to give specified mM/ml concentration
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    HA-1077 (Fasudil) (mM/ml), ROCK2 inhibitor
  • Description

    ROCK2 inhibitor. 1 ml water soluble pack.
  • Alternative names

    • Fasudil
  • Biological description

    ROCK2 inhibitor (IC50 = 1.9 µM). Also shown to inhibit PRK2 (IC50 = 4 µM), MSK1 (IC50 = 5 µM), Rsk2 (IC50 = 15 µM), PKA, p70 S6 Kinase, CaM Kinase and MLCK. Calcium antagonist and vasodilator.

    Soluble in 1 ml water to give specified mM/ml concentration. Find out more.

  • Purity

    > 98%
  • CAS Number

    103745-39-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-(5-Isoquinolinylsulfonyl)homopiperazine hydrochloride
  • Molecular weight

    327.83
  • Molecular formula

    C14H17N3O2S.HCl
  • PubChem identifier

    163751
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in 1ml of water to give specified mM/ml concentration
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Cl.O=S(=O)(c2cccc1cnccc12)N3CCCNCC3
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Huntington's disease
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