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Biochemicals

GYY 4137, H2S donor (ab142145)

Key features and details

  • Water-soluble, slow-releasing H2S donor
  • CAS Number: 106740-09-4
  • Purity: > 95%
  • Soluble in water to 75 mM and in DMSO to 25 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    GYY 4137, H2S donor
  • Description

    Water-soluble, slow-releasing H2S donor
  • Biological description

    Water-soluble, slow-releasing hydrogen sulfide donor. Inhibits LPS-induced release of proinflammatory intermediates and increases synthesis of IL-10. Exhibits novel anti-cancer effects. Vasodilator and antihypertensive activity. Active in vitro and in vivo
  • Purity

    > 95%
  • CAS Number

    106740-09-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    Morpholin-4-ium (4-methoxyphenyl)-morpholin-4-ylsulfanylidenesulfido-λ5-phosphane
  • Molecular weight

    376.47
  • Molecular formula

    C11H15NO2PS2.C4H10NO
  • PubChem identifier

    53393943
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 75 mM and in DMSO to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    COC1=CC=C(C=C1)P(=S)(N2CCOCC2)[S-].C1COCC[NH2+]1
  • Source

    Synthetic

  • Research areas

    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Immunomodulators & Immunosuppressants

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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