GYY 4137, H2S donor (ab142145)
Key features and details
- Water-soluble, slow-releasing H2S donor
- CAS Number: 106740-09-4
- Purity: > 95%
- Soluble in water to 75 mM and in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GYY 4137, H2S donor -
Description
Water-soluble, slow-releasing H2S donor -
Biological description
Water-soluble, slow-releasing hydrogen sulfide donor. Inhibits LPS-induced release of proinflammatory intermediates and increases synthesis of IL-10. Exhibits novel anti-cancer effects. Vasodilator and antihypertensive activity. Active in vitro and in vivo -
Purity
> 95% -
CAS Number
106740-09-4 -
Chemical structure
Properties
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Chemical name
Morpholin-4-ium (4-methoxyphenyl)-morpholin-4-ylsulfanylidenesulfido-λ5-phosphane -
Molecular weight
376.47 -
Molecular formula
C11H15NO2PS2.C4H10NO -
PubChem identifier
53393943 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 75 mM and in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=CC=C(C=C1)P(=S)(N2CCOCC2)[S-].C1COCC[NH2+]1 -
Source
Synthetic
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Research areas