Furosemide, Na+/2Cl-/K+ cotransporter inhibitor (ab120314)
Key features and details
- Inhibitor of the Na+/2Cl-/K+ cotransporter. Also GABAA antagonist.
- CAS Number: 54-31-9
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Furosemide, Na+/2Cl-/K+ cotransporter inhibitor -
Description
Inhibitor of the Na+/2Cl-/K+ cotransporter. Also GABAA antagonist. -
Biological description
Inhibitor of the Na+/2Cl-/K+ cotransporter. Loop diuretic. Also acts as a non-competitive antagonist at GABAA receptors displaying approx. 100-fold greater selectivity for α6-containing receptors over α1-containing receptors.
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Purity
> 99% -
CAS Number
54-31-9 -
Chemical structure
Properties
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Chemical name
5-(Aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]benzoic acid -
Molecular weight
330.74 -
Molecular formula
C12H11ClN2O5S -
PubChem identifier
3440 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
NS(=O)(=O)c2cc(c(NCc1ccco1)cc2Cl)C(=O)O -
Source
Synthetic
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Research areas
