RuBi-GABA, caged-GABA compound (ab120409)
Key features and details
- Novel caged-GABA compound, uncaged by visible light
- CAS Number: 1028141-88-9
- Soluble in DMSO to 25 mM. For water solubility, please refer to Guideline for Use Information Sheet
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
RuBi-GABA, caged-GABA compound -
Description
Novel caged-GABA compound, uncaged by visible light -
Biological description
Novel caged-GABA compound that uses a ruthenium complex as photosensor. Can be excited with visible wavelengths, providing greater tissue penetration, less photo-toxicity, and faster photorelease kinetics than other UV light-sensitive caged compounds. Can be used for GABA receptor mapping, and optical silencing of neuronal firing.
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General notes
RuBi-GABA is light sensitive and it is recommended that the compound is protected from light.
Sold under license from Columbia University; Patent Pending -
CAS Number
1028141-88-9 -
Chemical structure
Properties
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Chemical name
(Bis(2,2'-bipyridine-N,N')triphenylphosphine)-4-aminobutyric acid ruthenium hexafluorophosphate complex -
Molecular weight
922.80 -
Molecular formula
C42H39N5O2PRu.PF6 -
PubChem identifier
129316180 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 25 mM. For water solubility, please refer to Guideline for Use Information Sheet -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
[F-].FP(F)(F)(F)F.[O-]C(=O)CCC[NH2+][Ru]36(n1ccccc1c2ccccn23)(n4ccccc4c5ccccn56)P(c7ccccc7)(c8ccccc8)c9ccccc9 -
Source
Synthetic
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Research areas
