Fluphenazine hydrochloride, dopamine D2/D1 receptor antagonist (ab142300)
Key features and details
- Potent dopamine D2/D1 receptor antagonist
- CAS Number: 146-56-5
- Purity: > 97%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Fluphenazine hydrochloride, dopamine D2/D1 receptor antagonist -
Description
Potent dopamine D2/D1 receptor antagonist -
Biological description
Potent dopamine D2/D1 receptor antagonist (Ki values are 0.4 (D2), 2.3 (D1), 1.4 (D3), 7.1 (D4) and 25 nM (D5)). Inhibits dopamine-induced increases in adenylate cyclase activity (Ki = 9 nM). Antipsychotic. Active in vivo. -
Purity
> 97% -
CAS Number
146-56-5 -
Chemical structure
Properties
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Chemical name
2-[4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol dihydrochloride -
Molecular weight
510.44 -
Molecular formula
C22H25F3N3OS.2HCl -
PubChem identifier
67356 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO.Cl.Cl -
Source
Synthetic
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Research areas
