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Neuroscience Neurotransmitter Transporters GABA

Fipronil, GABA-gated Cl channel blocker (ab145201)

Key features and details

  • Potent GABA-gated Cl channel blocker
  • CAS Number: 120068-37-3
  • Purity: > 98%
  • Soluble in ethanol to 50 mM and in DMSO to 50 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Fipronil, GABA-gated Cl channel blocker
  • Description

    Potent GABA-gated Cl channel blocker
  • Biological description

    Potent GABA-gated Cl channel blocker (IC50 = 28 nM). Use as insecticide and in pesticide cytotoxicity studies. Apoptotic and necrotic potential. Active in vitro.
  • Purity

    > 98%
  • CAS Number

    120068-37-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl)pyrazole-3-carbonitrile
  • Molecular weight

    437.15
  • Molecular formula

    C12H4Cl2F6N4OS
  • PubChem identifier

    3352
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 50 mM and in DMSO to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F
  • Source

    Synthetic

  • Research areas

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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