Dutasteride, dual 5alpha reductase type 1 and type 2 inhibitor (ab141278)
Key features and details
- Selective, competitive dual 5α reductase type 1 and type 2 inhibitor
- CAS Number: 164656-23-9
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Dutasteride, dual 5alpha reductase type 1 and type 2 inhibitor -
Description
Selective, competitive dual 5α reductase type 1 and type 2 inhibitor -
Biological description
Selective, competitive dual 5α reductase type 1 and type 2 inhibitor. Blocks the conversion of testosterone into dihydrotestosterone. Shows antitumor effects in vivo. Orally active.
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Purity
> 99% -
CAS Number
164656-23-9 -
Chemical structure
Properties
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Chemical name
(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-
4a,6a-dimethyl-2-oxo-1H-Indeno[5,4-f]quinoline-7-carboxamide -
Molecular weight
528.53 -
Molecular formula
C27H30F6N2O2 -
PubChem identifier
6918296 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
FC(F)(F)c5cc(NC(=O)[C@H]4CC[C@@H]3[C@]4(C)CC[C@H]1[C@H]3CC[C@H]2NC(=O)C=C[C@]12C)c(cc5)C(F)(F)F -
Source
Synthetic
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Research areas
