Clorgyline hydrochloride, MAO-A inhibitor (ab145646)
Key features and details
- Selective, irreversible MAO-A inhibitor. Potent σ1 receptor inhibitor.
- CAS Number: 17780-75-5
- Purity: > 98%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Clorgyline hydrochloride, MAO-A inhibitor -
Description
Selective, irreversible MAO-A inhibitor. Potent σ1 receptor inhibitor. -
Biological description
Selective, irreversible MAO-A inhibitor (Ki values are 0.054 and 58 μM for MAO-A and MAO-B respectively). Potent σ1 receptor inhibitor (IC50 = 31 nM). Lysine-specific demethylase 1 inhibitor. Centrally active in vivo. -
Purity
> 98% -
CAS Number
17780-75-5 -
Chemical structure
Properties
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Chemical name
3-(2,4-Dichlorophenoxy)-N-methyl-N-prop-2-ynylpropan-1-amine hydrochloride -
Molecular weight
308.63 -
Molecular formula
C13H15Cl2NO.HCl -
PubChem identifier
28767 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(CCCOC1=C(C=C(C=C1)Cl)Cl)CC#C.Cl -
Source
Synthetic
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Research areas
