Cytochalasin C, actin polymerization inhibitor (ab143483)
Key features and details
- Cell permeable actin polymerization inhibitor. Mycotoxin.
- CAS Number: 22144-76-9
- Purity: > 98%
- Soluble in DMSO and in ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Cytochalasin C, actin polymerization inhibitor -
Description
Cell permeable actin polymerization inhibitor. Mycotoxin. -
Biological description
Cell permeable actin polymerization inhibitor. Mycotoxin. Increases TGF-β1 and collagenase transcription. Shows lower potency in vivo but similar potency in vitro to Cytochalasin D (ab143484). -
Purity
> 98% -
CAS Number
22144-76-9 -
Chemical structure
Properties
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Chemical name
(3S,3aR,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(Acetyloxy)-3,3a,6,6a,9,10,12,15-octahydro-6,12-dihydroxy-4,5,10,12-tetramethyl-3-(phenylmethyl)-1H-cycloundec[d]isoindole-1,11(2H)-dione -
Molecular weight
507.62 -
Molecular formula
C30H37NO6 -
PubChem identifier
2926 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO and in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1CC=CC2C(C(=C(C3C2(C(C=CC(C1=O)(C)O)OC(=O)C)C(=O)NC3CC4=CC=CC=C4)C)C)O -
Source
Synthetic
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Research areas
