CP 424174 (ab273388)
Key features and details
- Cytokine release inhibitory drug, IL-1β post-translational processing inhibitor
- CAS Number: 210825-31-3
- Purity: >= 98%
Soluble in DMSO to 75 mM and ethanol to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CP 424174 -
Description
Cytokine release inhibitory drug, IL-1β post-translational processing inhibitor -
Biological description
A cytokine release inhibitory drug (CRID). IL-1β inhibitor of post-translational processing and secretion in response to LPS and ATP in human monocytes (IC50 = 210nM). NLRP3 indirect inhibitor.
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Purity
>= 98% -
CAS Number
210825-31-3 -
Chemical structure
Properties
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Chemical name
N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide
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Molecular weight
452.99 -
Molecular formula
C22H29ClN2O4S -
PubChem identifier
9911728 -
Storage instructions
Shipped at 4°C. Store at -20°C. Store In the Dark. -
Solubility overview
Soluble in DMSO to 75 mM and ethanol to 75 mM
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Handling
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)C1=CC(=CC(=C1NC(=O)NS(=O)(=O)C2=CC=CC(=C2)C(C)(C)O)C(C)C)Cl -
Source
Synthetic