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Signal Transduction Signaling Pathway G Protein Signaling GPCR

CID 2745687, orphan receptor GPR35 inhibitor (ab141477)

Key features and details

  • Competitive, reversible orphan receptor GPR35 inhibitor
  • CAS Number: 264233-05-8
  • Purity: > 95%
  • Soluble in DMSO to 100 mM and in ethanol to 25 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    CID 2745687, orphan receptor GPR35 inhibitor
  • Description

    Competitive, reversible orphan receptor GPR35 inhibitor
  • Biological description

    Competitive, reversible orphan receptor GPR35 inhibitor (Ki = 12.8 nM). Inhibits GPR35-mediated increase in phosphorylation of ERK1/2.
  • Purity

    > 95%
  • CAS Number

    264233-05-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    Methyl 5-((2-t-butylcarbamothioyl)hydrazono)methyl)-1-(2,4-difluorophenyl)-1H-pyrazole-4-carboxylate
  • Molecular weight

    395.43
  • Molecular formula

    C17H19F2N5O2S
  • PubChem identifier

    2745687
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)(C)NC(=S)NN=CC1=C(C=NN1C2=C(C=C(C=C2)F)F)C(=O)OC
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • GPCR
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Orphan 7-TM Receptors

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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