Cathepsin G Inhibitor, cathepsin G inhibitor (ab142181)
Key features and details
- Cell-permeable, potent, selective, reversible, competitive cathepsin G inhibitor
- CAS Number: 429676-93-7
- Purity: > 98%
- Soluble in DMSO to 5 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Cathepsin G Inhibitor, cathepsin G inhibitor -
Description
Cell-permeable, potent, selective, reversible, competitive cathepsin G inhibitor -
Biological description
Cell-permeable, potent, selective, reversible, competitive cathepsin G inhibitor (IC50 = 0.53 μM). Ameliorates extracellular matrix damage and upregulates MMPs. Active in vitro and in vivo. -
Purity
> 98% -
CAS Number
429676-93-7 -
Chemical structure
Properties
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Chemical name
[2-[3-[(1-Benzoylpiperidin-4-yl)methylcarbamoyl]naphthalen-2-yl]-1-naphthalen-1-yl-2-oxoethyl]phosphonic acid -
Molecular weight
620.63 -
Molecular formula
C36H33N2O6P -
PubChem identifier
9830518 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 5 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(C1CCN(CC1)C(=O)C2=CC=CC=C2)C(=O)C3=CC4=CC=CC=C4C=C3C(=O)C(C5=CC=CC6= CC=CC=C65)P(=O)(O)O -
Source
Synthetic
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Research areas