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Biochemicals

Catharanthine, monomeric precursor to Vincristine and vinblastine (ab141419)

Key features and details

  • Monomeric precursor to Vincristine and vinblastine
  • CAS Number: 2468-21-5
  • Purity: > 98%
  • Soluble in DMSO to 10 mM
  • Form / State: Solid
  • Source: Catharanthus roseus

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Overview

  • Product name

    Catharanthine, monomeric precursor to Vincristine and vinblastine
  • Description

    Monomeric precursor to Vincristine and vinblastine
  • Biological description

    Monomeric precursor to Vincristine (ab120226) and vinblastine (ab141475). Weakly affects bipolar mitotic spindle formation. Shows weak tubulin polymerization inhibition and weak cytotoxic effects.
  • Purity

    > 98%
  • CAS Number

    2468-21-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    Methyl (2α,5β,6α)-3,4-didehydroibogamine-18β-carboxylate
  • Molecular weight

    336.43
  • Molecular formula

    C21H24N2O2
  • PubChem identifier

    418553
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCC1=CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC
  • Source

    Catharanthus roseus

  • Research areas

    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Research Area
    • Cancer
    • Apoptosis & cell cycle
    • Other
    • Biochemicals
    • Pharmacology
    • Signaling
    • Cytoskeleton & motor proteins
    • Tubulin

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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