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Calhex 231, negative allosteric modulator of calcium sensing receptors (ab254526)

Key features and details

  • Negative allosteric modulator of calcium-sensing receptor
  • CAS Number: 652973-93-8

  • Soluble in DMSO to 50 mM

  • Form / State: Solid
  • Source: Synthetic

Overview

  • Product name

    Calhex 231, negative allosteric modulator of calcium sensing receptors

  • Description

    Negative allosteric modulator of calcium-sensing receptor

  • Biological description

    Negative allosteric modulator of calcium-sensing receptor (CaSR). CaSR calcilytic. Blocks (IC50 = 0.39 μM) increases in [3H]inositol phosphates due to CaSR activation.

  • CAS Number

    652973-93-8

  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]benzamide

  • Molecular weight

    406.95

  • Molecular formula

    C25H27ClN2O

  • PubChem identifier

    11849514

  • Storage instructions

    Shipped at room temperature. Store at -20°C.

  • Solubility overview

    Soluble in DMSO to 50 mM

  • Handling

    Refer to SDS for more information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C[C@H](C1=CC=CC2=CC=CC=C21)N[C@H]3CCCC[C@@H]3NC(=O)C4=CC=C(C=C4)Cl

  • Source

    Synthetic

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