Calhex 231, negative allosteric modulator of calcium sensing receptors (ab254526)
Key features and details
- Negative allosteric modulator of calcium-sensing receptor
- CAS Number: 652973-93-8
Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Calhex 231, negative allosteric modulator of calcium sensing receptors -
Description
Negative allosteric modulator of calcium-sensing receptor -
Biological description
Negative allosteric modulator of calcium-sensing receptor (CaSR). CaSR calcilytic. Blocks (IC50 = 0.39 μM) increases in [3H]inositol phosphates due to CaSR activation.
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CAS Number
652973-93-8 -
Chemical structure
Properties
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Chemical name
4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]benzamide
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Molecular weight
406.95 -
Molecular formula
C25H27ClN2O -
PubChem identifier
11849514 -
Storage instructions
Shipped at room temperature. Store at -20°C. -
Solubility overview
Soluble in DMSO to 50 mM
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Handling
Refer to SDS for more information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@H](C1=CC=CC2=CC=CC=C21)N[C@H]3CCCC[C@@H]3NC(=O)C4=CC=C(C=C4)Cl -
Source
Synthetic
