C59, Wnt Antagonist, Wnt signaling pathway inhibitor (ab142216)
Key features and details
- Potent, cell-permeable Wnt signaling pathway inhibitor
- CAS Number: 1243243-89-1
- Purity: > 97%
- Soluble in ethanol to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
C59, Wnt Antagonist, Wnt signaling pathway inhibitor -
Description
Potent, cell-permeable Wnt signaling pathway inhibitor -
Biological description
Potent Wnt signaling pathway inhibitor. Inhibits porcupine (PORCN) required for Wnt palmitoylation, secretion, and biological activity. Inhibits Wnt-mediated transcription (IC50 = 74 pM) and cell proliferation. Active in vivo.
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Purity
> 97% -
CAS Number
1243243-89-1 -
Chemical structure
Properties
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Chemical name
2-[4-(2-Methylpyridin-4-yl)phenyl]-N-[4-(pyridin-3-yl)phenyl]acetamide -
Molecular weight
379.45 -
Molecular formula
C25H21N3O -
PubChem identifier
57519544 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 10 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1C2C(C2C3=C(N1CC4=CC=CC=C4)N=C5C=CC=CN5C3=O)C6=CC=CC=C6 -
Source
Synthetic
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Research areas
